Network Meta-analysis of Clinical Characteristics of 81 Patients with Pulmonary Sequestration and Different Treatment Methods for Pulmonary Sequestration
Objective To summarize the clinical characteristics of pulmonary sequestration by integrating the results of clinical research and network meta-analysis,and to compare the advantages and disadvantages of different treatment methods,so as to provide certain reference information for clinical work.Methods The clinical characteristics of 81 patients with pulmonary sequestration in Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology were retrospectively analyzed,and the efficacy of thoracotomy and thoracoscopic surgery was compared.Relevant literatures were re-trieved for network meta-analysis to compare the efficacy and safety of interventional therapy,thoracoscopic surgery,and thora-cotomy in the treatment of pulmonary sequestration.Results A total of 81 patients were included in the single-center retrospec-tive study,including 38 in the thoracotomy group and 43 in the thoracoscopic group.In terms of surgical years,the number of patients in the thoracotomy group was more than that in the thoracoscopic group before 2016,and less than that in the thoraco-scopic group after 2017(all P＜0.05).The postoperative hospital stay in the thoracoscopic group was shorter than that in the thoracotomy group(both P＜0.05).A total of 12 records involving 591 patients were included in the network meta-analy-sis.The operation time of the interventional group was shorter than that of the thoracoscopic group and the thoracotomy group.The intraoperative blood loss in the interventional group was less than that in the thoracoscopic group and the thoracoto-my group.The intraoperative blood loss in the thoracoscopic group was less than that in the thoracotomy group.The postopera-tive hospital stay in the interventional group was shorter than that in the thoracoscopic group and the thoracotomy group.The postoperative hospital stay in the thoracoscopic group was shorter than that in the thoracotomy group(all P＜0.05).Conclusion Compared with traditional thoracotomy and thoracoscopic surgery,interventional therapy for pulmonary sequestration has shor-ter operation time,less intraoperative blood loss,and shorter postoperative hospital stay.
万方数据
维普
