Objective:To explore the effects of BiPAP noninvasive ventilator combined with routine treatment on serum N-terminal B-type brain natriuretic peptide precursor(NT proBNP),lung function,and blood gas analysis indicators in patients with chronic pulmonary heart disease(CPHD).Methods:Sixty patients with CPHD from the Third Hospital of Pingx-iang City from January 2020 to December 2022 were selected and randomly divided into a control group(30 cases)and an observation group(30 cases)using a number table method.The control group received routine treatment,while the observa-tion group received BiPAP noninvasive ventilation combined with treatment.Before and seven days after treatment,serum NT proBNP levels,lung function indicators(forced expiratory volume in one second(FEV1),forced vital capacity(FVC),and their ratio(FEV1/FVC),blood gas analysis indicators(arterial partial pressure of carbon dioxide(PaCO2),arterial partial pressure of oxygen(PaO2),and pH)were measured and compared between the two groups.Before treatment,there was no statistically significant difference in the NT-proBNP,FVC,FEV1,FEV1/FVC,PaCO2,PaO2,and pH levels between the two groups(P＞0.05).After seven days of treatment,the serum levels of NT-proBNP and PaCO2 in both groups decreased,and the observation group was lower than the control group.FVC,FEV1,FEV1/FVC,PaO2,and pH in both groups increased,and the observation group was higher than the control group,with a statistically significant difference(P＜0.05).Conclusions:Bi-PAP noninvasive ventilator combined with routine treatment significantly improves the NT proBNP levels,lung function,and blood gas analysis indicators in patients with CPHD.
维普
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