Advances in molecular networking based on LC-MS/MS
Molecular networking(MN)is a method based on liquid chromatography-mass spectrometry(LC-MS/MS)that can be used to analyze mass spectrometry data in a short period of time,identify known compounds,and identify various unknown natural products and their metabolites.This article focuses on the concept of molecular networks and briefly introduces the steps involved in their construction.Subsequently,the application scope of molecular networks was elaborated from five aspects:rapid identification of known,unknown,and similar chemical components;characterization and quality control of chemical component differences;guidance on purification and separation of chemical components;integration of molecular networks with new strategies in network pharmacology;and Feature-based Molecular Networking.Finally,this study forecasted the prospects of molecular networking,aiming to be more widely applied and to promote the development and innovation of modern scientific research.
万方数据
维普
