Clinical observation on acupuncture combined with antiemetic drugs in the treatment of chemotherapy-induced nausea and vomiting in gastric cancer patients
[Objective]This study aimed to explore the effectiveness of acupuncture in treatment of chemotherapy-induced nausea and vomiting(CINV)among advanced cancer patients receiving chemotherapy.[Methods]Gastric cancer patients who were hospitalized from January 2022 to December 2023 were collected.According to whether it was acupuncture treatment during chemotherapy,all patients were divided into the antiemetic drugs group and the acupuncture with antiemetic drugs group.The observational indexes were the incidence of acute nausea and vomiting and delayed nausea and vomiting,the total number of nausea and vomiting during chemotherapy,quality of life,safety,and antiemetic drug-related adverse reactions.[Results]Compared with the antiemetic drugs group,the acupuncture with antiemetic drugs group can reduce acute and delayed CINV(P＜0.05),and the frequency of nausea and vomiting were decreased in this group(P＜0.05).The ECOG-KPS score in the the acupuncture with antiemetic drugs group was significantly improved(P=0.028).Acupuncture had higher safety.In addition,the adverse events of antiemetic drugs,such as constipation(P=0.031)and diarrhea(P=0.005),were decreased by acupuncture.[Conclusion]Acupuncture combined with antiemetics could reduce the incidence of CIN V,improve the quality of life of patients,and reduce the incidence of adverse side effects of antiemetic drugs.
gastric cancerchemotherapy-induced nausea and vomitingacupunctureantiemetic drugcurative effect
万方数据
维普
