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中药药效物质及靶点发现新技术的研究进展

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科学技术的不断进步推动了中医药现代化研究的进程.然而,在复杂的中药体系中,药效物质难以辨识、作用靶标表征困难等瓶颈问题仍然存在.因此,文章旨在整合近年来中药药效物质筛选及药效靶点发现领域的新技术,以期能够为药效物质发现和药理机制探究提供新的参考,为进一步加快中药现代化进程提供新的见解.
Research progress of new technologies for the discovery of pharmacodynamic substances and targets in Chinese medicines
The continuous advancement of science and technology has facilitated the modernization research of traditional Chinese medicine.However,within the complex system of traditional Chinese medicine,the challenges such as the difficulty in identifying pharmacodynamic substances and targets still exist.Therefore,the aim of this paper is to integrate the new technologies in the fields of pharmacodynamic substance screening and pharmacodynamic target discovery of traditional Chinese medicine in recent years,in order to provide new references for the discovery.

modernization of traditional Chinese medicinepharmacodynamic substancestargets discoverynew technologies

赵露、张舒静、王毅

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天津中医药大学中医药研究院,天津 301617

浙江大学药学院中药科学与工程学系,杭州 310058

组分中药国家重点实验室,天津 301617

中医药现代化 药效物质 靶标发现 新技术

浙江省"尖兵""领雁"研发攻关计划项目浙江省自然科学基金资助项目

2023C03004LQ24H280012

2024

天津中医药
天津市中医药大学,天津中西医结合学会,天津中医药学会

天津中医药

CSTPCD
影响因子:0.998
ISSN:1672-1519
年,卷(期):2024.41(10)
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