Systematic review and meta-analysis of the effect of Baduanjin on pre-diabetic patients
[Objective]To systematically evaluate the effect of Baduanjin exercise on patients with pre-diabetes(PDM).[Methods]Computer retrieval of PubMed,Embase,CochraneLibrary,CBM,CNKI,WanFang,and VIP databases was conducted to collect randomized controlled trials(RCTs)on the impact of Baduanjin exercise on PDM patients.The retrieval time was from the database establishment until September 2022.Two researchers indepen-dently screened the literature,extracted the data,and evaluated the risk of bias included in the study.Then,a meta-analysis was conducted using Revman 5.4.1 software.[Results]A total of 11 RCT studies were included,including 665 patients.Meta analysis results showed that:1)In terms of glucose metabolism,compared with the control group,the Baduanjin exercise can reduce fasting blood glucose[MD=-0.46,95%CI(-0.60,-0.31),P<0.01],glycated hemoglobin[MD=-0.46,95%CI(-0.82,-0.10),P=0.01],fasting insulin[MD=-1.32,95%CI(-2.06,-0.57),P= 0.0005],and insulin resistance index[MD=-0.60,95%CI(-0.87,-0.33),P<0.01].2)In terms of body improve-ment,compared with the control group,Baduanjin exercise can reduce body mass index[MD=-1.04,95%CI(-1.28,-0.80),P<0.01];The results of subgroup analysis of waist to hip ratio indicators indicate that compared with the con-ventional treatment group,the Baduanjin exercise can reduce the waist to hip ratio of PDM patients[MD=-0.03,95%CI(-0.04,-0.02),P<0.01].Compared with the control group of walking or walking,there is no statistically sig-nificant difference in the waist to hip ratio between the two groups[MD=-0.01,95%CI(-0.03,-0.01),P=0.43].3)In terms of improving quality of life,compared with the control group,Baduanjin exercise can improve physiological health scores[MD=8.68,95%CI(5.06,12.29),P<0.01]and psychological health scores[MD=6.95,95%CI(4.86,9.04),P<0.01].[Conclusion]Current evidence shows that Baduanjin exercise can improve fasting blood glucose,glycated hemoglobin,fasting insulin,and insulin resistance index in PDM patients,reduce body mass index and waist to hip ratio,improve physical and mental health scores,and have good safety.It has good promotion and appli-cation value for PDM patients.However,due to the limitations of the number and quality of included studies,the above conclusions still need to be further validated through more high-quality randomized controlled clinical trials.
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