Research progress on pharmacological effects of Sini San and predictive analysis of its quality markers
Sini San is composed of Prepared glycyrrhiza,Radix bupleuri,Radix paeoniae alba,Citrus aurantium L,Aurantii fructus immaturus.It has the effect of removing pathogenic factors and relieving depression,soothing the liver and regulating the spleen.Modern pharmacological studies have shown that the drug has anti-depression,liver protection,treatment of functional dyspepsia,improvement of arteriosclerosis,sedative-hypnotic and anti-ulcer effects.On the basis of summarizing the research progress of pharmacological effects of Sini San,the quality marker of Sini San was predicted and analyzed according to the"five principles"of Q-marker in traditional Chinese medicine.The results suggested that liquiritin,liquiritigenin,glycyrrhetinic acid,glycyrrhizic acid,kaempferol,quercetin,naringin,saikosaponin a,saikosaponin d,paeoniflorin,albiflorin,hesperidin,neohesperidin,synephrine could be used as quality markers of Sini San,in order to provide reference for the quality control of Sini San.
Sini Sanpharmacological effectquality markerquality control