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生脉饮的化学成分、药理作用和临床应用进展

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生脉饮是由红参、麦冬、五味子3味药组成的常用中药经典方剂,具有益气复脉、养阴生津的作用.现代研究发现,生脉饮的化学成分主要包括皂苷类、木脂素类、高异黄酮类、多糖类和有机酸类等.相关药理学实验研究表明,生脉饮具有抗心律失常、抗心力衰竭、抗肿瘤等药理作用,临床上常与各类常规治疗药物联合使用发挥疗效,从而改善患者的临床症状.文章对近年来生脉饮的化学成分、药理作用和临床应用的研究进行了系统的阐述,以期为该方剂的进一步研究及开发利用提供支持和参考.
Progress on chemical constituents,pharmacological effects and clinical applications of Shengmaiyin
Shengmaiyin is a commonly used traditional Chinese medicine classic formula composed of Red ginseng,Ophiopogon and Schisandra chinensis,with effects of benefiting qi and restoring pulse,astringing yin and promoting fluid.Modern studies indicate that the chemical constituents of Shengmaiyin mainly include saponins,lignans,homoisoflavones,polysaccharides,organic acids and so on.Related pharmacological experimental studies have shown that Shengmaiyin has anti-arrhythmia,heart failure,anti-tumor and other pharmacological effects.It is often used in combination with various conventional therapeutic drugs to exert clinical efficacy,improve the patient's clinical symptoms.In this review,the research on the chemical constituents,pharmacological effects and clinical applications of Shengmaiyin have been systematically summarized,in order to provide support and reference for the further research and development of this prescription.

Shengmaiyinchemical constituentpharmacological effectclinical application

王萍、赵姿雯、王丁丁、王韦博、李蕊汐、陈宇洲

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天津中医药大学中药学院,天津 301617

天津市中药功效物质重点实验室,天津 301617

生脉饮 化学成分 药理作用 临床应用

天津市研究生科研创新项目天津中医药大学研究生科研创新项目资助项目

2021YJSS187YJSKC-20212011

2024

天津中医药大学学报
天津中医药大学

天津中医药大学学报

CSTPCD
影响因子:1.324
ISSN:1673-9043
年,卷(期):2024.43(6)
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