首页|卵巢癌患者肿瘤细胞减灭术后尿路感染风险评估模型的建立与效果检验

卵巢癌患者肿瘤细胞减灭术后尿路感染风险评估模型的建立与效果检验

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目的 构建卵巢癌患者肿瘤细胞减灭术后尿路感染风险评估模型,检验其评估效果.方法 选取医院2021年2月-2022年2月收治的行肿瘤细胞减灭术的卵巢癌患者112例为研究对象,采用一般资料量表调查患者信息,统计术后尿路感染的患者例数,通过单因素分析、多因素Logistic回归分析筛选术后尿路感染的影响因素,根据回归分析结果构建尿路感染风险评估模型,并经应用检验其效果.结果 统计显示,肿瘤细胞减灭术后出现尿路感染的卵巢癌患者24例,发生率为21.43%.多因素Logistic回归分析显示,卵巢癌患者肿瘤细胞减灭术后尿路感染影响因素有年龄、合并糖尿病、手术时间、术中失血量、术后导尿管留置时间、导尿管插管次数、术后低蛋白血症、尿路感染预防宣教(P<0.05).其中,年龄≥ 65岁、合并糖尿病、导尿管留置时间≥7 d、导尿管插管次数>1次、术后低蛋白血症、尿路感染预防宣教缺失的术后患者更容易发生尿路感染.根据Logistic回归分析结果构建卵巢癌患者肿瘤细胞减灭术后尿路感染风险评估模型,模型Hosmer-Lemeshow检验显示,差异无统计学意义(x2=2.848,P=0.132),模型拟合优度表现良好;模型ROC曲线AUC为0.805,95%CI为0.729~0.877,最大约登指数为0.649,对应灵敏度、特异度分别为0.802、0.847;临床应用检验显示,模型预测准确率为91.96%.结论 卵巢癌患者肿瘤细胞减灭术后伴有不同程度的尿路感染风险,年龄、合并糖尿病、手术时间、术中失血量、术后导尿管留置时间、导尿管插管次数、术后低蛋白血症、尿路感染预防宣教为卵巢癌患者肿瘤细胞减灭术后尿路感染影响因素,构建的模型能有效识别卵巢癌肿瘤细胞减灭术后尿路感染风险,为临床预防护理提供参考,以增强护理针对性,进而降低尿路感染发生率.
Establishment and effectiveness testing of a risk assessment model for urinary tract infection in patients with ovarian cancer after cytoreductive surgery
Objective To construct a risk assessment model for urinary tract infection in patients with ovarian cancer after cytoreductive surgery and test its assessment effect.Methods We selected 112 ovarian cancer patients who underwent cytoreductive surgery in the hospital from February 2021 to February 2022 as the research subjects,used a general information scale to investigate patient information,and counted the number of patients with postoperative urinary tract infection,and screened the influencing factors of postoperative urinary tract infection through univariate analysis and multivariate Logistic regression analysis,constructed a urinary tract infection risk assessment model based on the regression analysis results,and tested its effect through application.Results Statistics showed that 24 ovarian cancer patients developed urinary tract infection after cytoreduction,with an incidence rate of 21.43%.Multivariate Logistic regression analysis showed that the age,diabetes mellitus,operation time,intraoperative blood loss,postoperative catheter indwelling time,catheter intubation times,postoperative hypoalbuminemia,and education on urinary tract infection prevention were influencing factors of urinary tract infection in patients with ovarian cancer after cytoreductive surgery(P<0.05).Among them,postoperative patients who were ≥65 years old,had diabetes,had a urinary catheter indwelling for ≥7 days,had catheterizations>1 times,had postoperative hypoalbuminemia,and lack of education on urinary tract infection prevention were more likely to develop urinary tract infection.Based on the results of logistic regression analysis,a urinary tract infection risk assessment model for ovarian cancer patients after cytoreductive surgery was constructed.The Hosmer-Lemeshow test of the model showed that the difference was not statistically significant(x2=2.848,P=0.132),and the goodness of fit of the model was good;the AUC of the model ROC curve was 0.805,the 95%CI was 0.729~0.877,the maximum Youden index was 0.649,and the corresponding sensitivity and specificity were 0.802 and 0.847 respectively;clinical application testing showed that the model prediction accuracy was 91.96%.Conclusion Patients with ovarian cancer were associated with varying degrees of risk of urinary tract infection after cytoreductive surgery,the age,diabetes mellitus,operation time,intraoperative blood loss,postoperative catheter indwelling time,catheter intubation times,postoperative hypoalbuminemia,and education on urinary tract infection prevention were influencing factors of urinary tract infection in patients with ovarian cancer after cytoreductive surgery.The constructed model can effectively identify the risk of urinary tract infection after cytoreduction for ovarian cancer,and provide a reference for clinical preventive care to enhance the pertinence of care and thereby reduce the incidence of urinary tract infection.

Ovarian cancerCytoreductive surgeryUrinary tract infectionRisk assessment modelCatheter intubation

李梦铃、黎婉弟、甄春华、陈华敏、谢露茵

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中山大学肿瘤防治中心(广东省广州市,510060)

卵巢癌 肿瘤细胞减灭术 尿路感染 风险评估模型 导尿管插管

2024

护理实践与研究
河北省儿童医院

护理实践与研究

影响因子:1.354
ISSN:1672-9676
年,卷(期):2024.21(2)
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