首页|集束化护理模式对肿瘤患者骨髓抑制期有效性的Meta分析

集束化护理模式对肿瘤患者骨髓抑制期有效性的Meta分析

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目的 系统评价集束化护理对肿瘤患者骨髓抑制的效果.方法 检索国内外中英文数据库,纳入有关集束化护理干预对骨髓抑制效果的随机对照试验(RCT),对文献进行质量评价,本研究采用RevMan 5.4统计软件进行数据分析.结果 共纳入25篇RCT,其中中文23篇,英文2篇,共2072例患者.Meta分析结果显示,试验组(集束化护理措施)降低感染的发生率为RR=0.43,95%CI:0.36~0.50,P<0.00001;出血发生率RR=0.33,95%CI:0.24~0.46,P<0.00001;发热发生率 RR=0.54,95%CI:0.44~0.67,P<0.00001;改善患者心理状态焦虑水平 MD=-2.88,95%CI:-3.65~-2.11,P<0.00001;抑郁水平 MD=-1.49,95%CI:-12.06~-0.92,P<0.00001 以及提高患者满意度RR=1.25,95%CI:1.15~1.35,P<0.00001,均高于对照组,组间比较差异有统计学意义(P<0.05).结论 集束化护理可以预防肿瘤患者骨髓抑制期并发症的发生,同时改善患者心理状态,提高患者的满意度.
Meta-analysis of the effectiveness of the cluster nursing model on myelosuppression in cancer patients
Objective To systematically evaluate the effect of cluster nursing on myelosuppression in cancer patients.Methods We searched Chinese and English databases at home and abroad,included randomized controlled trials(RCT)on the effect of cluster nursing intervention on myelosuppression,and evaluated the quality of the literature.This study used RevMan 5.4 statistical software for data analysis.Results A total of 25 RCT were included,including 23 Chinese and 2 English,with a total of 2,072 patients.The Meta-analysis results showed that in the experimental group(cluster nursing measures),the incidence rate of infection was reduced byRR=0.43,95%CI:0.36~0.50,P<0.00001;the incidence rate of bleeding was RR=0.33,95%CI:0.24~0.46,P<0.00001;the incidence rate of fever was RR=0.54,95%CI:0.44~0.67,P<0.00001;the patient's psychological state,anxiety level,MD=-2.88,95%CI:-3.65~-2.11,P<0.00001,and depression level,MD=-1.49,95%CI:-12.06~-0.92,P<0.00001,and improved patient satisfaction RR=1.25,95%CI:1.15~1.35,P<0.00001,both higher than the control group,and the differences between the groups were statistically significant(P<0.05).Conclusion Cluster nursing can prevent the occurrence of complications in the myelosuppression phase of cancer patients,while improving the patient's psychological state and improving patient satisfaction.

TumorMyelosuppressionCluster nursingEffectivenessMeta-analysis

李成成、殷利、向明芳、张萱、吕俭霞

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四川省肿瘤医院/四川省癌症防治中心/电子科技大学医学院(四川省成都市,610041)

肿瘤 骨髓抑制 集束化护理 有效性 Meta分析

2022年四川省省级临床重点专科建设项目

YB2022009

2024

护理实践与研究
河北省儿童医院

护理实践与研究

影响因子:1.354
ISSN:1672-9676
年,卷(期):2024.21(2)
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