Effect of clustered oral care management on reducing radiation-induced oral mucositis response in nasopharyngeal carcinoma patients undergoing intensity modulated radiation therapy
Objective To evaluate the effect of a clustered oral management program on radiotherapy-induced oral mucositis(RTOM)response in daytime nasopharyngeal carcinoma patients undergoing intensity modulated radiation therapy.Methods A total of 200 nasopharyngeal carcinoma patients undergoing intensity-modulated radiation therapy who received daytime therapy in the hospital from January to December 2021 were selected as the research subjects.According to the principle of comparability of basic characteristics between the groups,they were divided into an observation group and a control group,with 100 cases in each group.The control group implemented routine nursing care,while the observation group adopted clustered oral care management on this basis.The differences in oral mucositis,pain levels of dry mouth and oropharynx,quality of life,and medication adherence between the two groups of patients were compared.Results After the intervention,the severity of oral mucositis in the observation group was lower than that in the control group,and the difference between the groups was statistically significant(P＜0.05);the scores for dry mouth and oropharyngeal pain in the observation group were lower than those in the control group,and the differences between the groups were statistically significant(P＜0.05).Before intervention,there was no statistically significant difference in scores of physiological function,physiological role,body pain,general health,vitality,social function,emotional role,and mental health between the two groups(P＞0.05).After the intervention,the scores of the observation group were higher than those of the control group in seven dimensions:physiological function,physiological role,general health status,energy,social function,emotional role,and mental health,the body pain score of the observation group was lower than that of the control group,and the differences were statistically significant(P＜0.05).After the intervention,the oral medication compliance of patients in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion The implementation of a clustered oral management program for nasopharyngeal carcinoma patients undergoing intensity modulated radiation therapy can effectively delay and reduce the occurrence of radiation-induced oral mucosal response,and can also alleviate the problems of dry mouth and oropharyngeal pain during treatment,thereby improving the patients'quality of life and oral medication compliance.
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