Analysis of the predictive effect of the Caprini risk assessment model on port-related venous thrombosis in patients with breast cancer undergoing chemotherapy
Objective To explore the predictive effect of the Caprini risk assessment model on port-related venous thrombosis in patients with breast cancer undergoing chemotherapy.Methods A total of 300 breast cancer patients undergoing chemotherapy with infusion port admitted to the hospital from May 2018 to May 2022 were selected for the study.Among them,60 breast cancer patients with confirmed infusion port-related venous thrombosis were included in the occurrence group,while 240 breast cancer patients without infusion port-related venous thrombosis were included in the non-occurrence group.The general information of all patients was collected,and the Caprini risk assessment model was used to score and categorize the risk levels of both groups.A multivariate logistic regression model was employed to analyze the factors influencing infusion port-related venous thrombosis in patients with breast cancer chemotherapy,and the value of the Caprini risk assessment model in predicting infusion port-related venous thrombosis in these patients was explored.Results The results of binary Logistic regression analysis showed that the age,long-term bed rest,duration of infusion port placement,previous history of venous thrombosis,distant metastasis,comorbidities,lower limb edema,D-D level before puncture,CRP level before puncture,Caprini risk assessment model scores and its risk grading were influencing factors for infusion port-related venous thrombosis in breast cancer patients undergoing chemotherapy(P<0.05).Among these factors,breast cancer chemotherapy patients with age≥60 years old,long-term bed rest,duration of infusion port placement≥1 year,previous history of venous thrombosis,distant metastasis,comorbidities,lower limb edema,D-D level before puncture,CRP level before puncture,and Caprini risk assessment model score>9.5 points were more likely to suffer from infusion port-related venous thrombosis.ROC curve analysis showed that the AUC of Caprini risk assessment model score for predicting infusion port-related venous thrombosis in breast cancer patients undergoing chemotherapy was 0.807,with a cut-offvalue of 9.5 points.The sensitivity and specificity were 55.0%and 92.1%,respectively.Conclusion The age,long-term bed rest,duration of infusion port placement,previous history of venous thrombosis,distant metastasis,comorbidities,lower limb edema,D-D level before puncture,CRP level before puncture,and Caprini risk assessment model scores were influencing factors for infusion port-related venous thrombosis in breast cancer patients undergoing chemotherapy.The Caprini risk assessment model has significant value in predicting infusion port-related venous thrombosis in breast cancer patients undergoing chemotherapy.
Breast cancerChemotherapyInfusion portRelated venous thrombosisCaprini risk assessment modelInfluencing factorsPredictive value
万方数据
维普
