Research progress of traditional Chinese medicine intervention in cancer immune escape
Immune escape refers to the process in which malignant tumor cells have malignant biological behaviors such as in-filtration and metastasis after immune editing,and escape the surveillance and clearance of the immune system,which ulti-mately promotes the occurrence and development of malignant tumor.Among other factors,immune cells actively influence ev-ery step of tumor development,determining cancer cells'chances of survival in a threatened microenvironment.Once the first cancer cell is found,anti-tumor immune mechanisms are activated and play a role in primary tumor formation and metastasis.However,when immune function is impaired,tumor cells will promote their own proliferation by evading or obstructing the mechanism of immune response,which will lead to the sustainable development of tumors.The mechanism of traditional Chi-nese medicine intervention in cancer immune escape should be based on the basic principle of"Fuzheng",supplementing the healthy qi to cure its root,enhancing the lethality of immune cells to cancer cells,preventing cancer immune escape,and thus inhibiting the development of cancer.According to the analysis of existing literature,at present,cancer is treated with many supplements through immune escape,which may be because the immune regulation function of the body is consistent with the view of"Fuzheng"in traditional Chinese medicine.Therefore,the study of cancer immune escape mechanism can not only improve the efficiency of cancer treatment,but also delay the development of the disease and better improve the quality of life of patients through the development and utilization of traditional Chinese medicine.
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