天然产物研究与开发2024,Vol.36Issue(3) :485-498.DOI:10.16333/j.1001-6880.2024.3.012

基于炮制前后质量一致性的清半夏炮制新工艺评价

Evaluation of new processing technology of Pinelliae Rhizoma Praeparatum cum Alumine based on quality consistency before and after processing

颜雨豪 殷莉丽 黎智 蒋孟莲 杨转珍 万子玉 赖月月 李敏
天然产物研究与开发2024,Vol.36Issue(3) :485-498.DOI:10.16333/j.1001-6880.2024.3.012

基于炮制前后质量一致性的清半夏炮制新工艺评价

Evaluation of new processing technology of Pinelliae Rhizoma Praeparatum cum Alumine based on quality consistency before and after processing

颜雨豪 1殷莉丽 1黎智 1蒋孟莲 1杨转珍 1万子玉 1赖月月 1李敏1
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作者信息

  • 1. 成都中医药大学 药学院/现代中药产业学院 省部共建西南特色中药资源国家重点实验室,成都 611137
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摘要

为研究半夏与清半夏的质量传递关系,并评价新工艺蒸法所得炮制品与清半夏的质量一致性,本研究检测了生半夏及3种炮制品的浸出物、有机酸、多糖、核苷、蛋白质含量,使用主成分分析等方法比较3种炮制品的差异.结果表明,与生半夏相比,浸、煮制清半夏的浸出物减少,而蒸制品浸出物增加了 264.76%;总酸、多糖含量均显著增加,其中蒸制品的增幅最大;核苷、蛋白质含量均大幅降低;综合分析方法均表明蒸制品与传统方法所得清半夏存在较大的质量差异.由此可知,浸、煮制清半夏质量一致性较好,而蒸法炮制品仍需对其加工工艺、药效做进一步研究.

Abstract

To investigate the quality transfer relationship between Pinellia Rhizoma(PR)and Pinelliae Rhizoma Praeparatum cum Alumine(PRPA),as well as to assess the consistency in quality between the newly processed product using steam pro-cessing and PRPA,this study examined the leachate,organic acids,polysaccharides,nucleosides,and protein content of raw PR and three processed products.Differences among the three processed products were compared using methods such as prin-cipal component analysis.The results indicated notable differences in quality between the steamed product and traditional con-coctions of PR.Compared to raw PR,the extracts from soaking and boiling decreased,while the extract from steaming in-creased by 264.76%.Total organic acid and polysaccharide content significantly increased,especially in the steamed prod-uct.Nucleoside and protein content,however,experienced substantial reduction.Hence,it can be inferred that the quality con-sistency of soaked and boiled PRPA is relatively high,while further research is needed to explore the processing techniques and medicinal effects of the steamed products.

关键词

半夏/清半夏/炮制工艺/质量传递/主成分分析/一致性

Key words

Pinellia Rhizoma/Pinelliae Rhizoma Praeparatum cum Alumine/processing technique/quality transfer/principal component analysis/consistency

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基金项目

四川省科技厅科技项目(2021ZHCG0067)

出版年

2024
天然产物研究与开发
中国科学院成都文献情报中心

天然产物研究与开发

CSTPCD北大核心
影响因子:0.783
ISSN:1001-6880
参考文献量23
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