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乌药中3个新的倍半萜

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研究乌药的化学成分.采用硅胶、ODS、Sephadex LH-20、制备液相等多种色谱分离技术进行分离纯化,通过波谱数据分析进行结构鉴定.从乌药90%乙醇提取物中分离得到4个倍半萜,分别鉴定为linderaggredin B1(1)、乌药酮酸A(2)、乌药酮酸B(3)、chlorahupetolide K(4),其中化合物1~3为新化合物,化合物4为首次从樟科中分离得到.
Three new sesquiterpenoids from Linderae Radix
To study the chemical constituents of Linderae Radix,three new compounds,named linderaggredin B1(1),linde-nonic acid A(2),and lindenonic acid B(3),along with one know compound chlorahupetolide K(4)were isolated from the 90%EtOH extract of Linderae Radix by various chromatographic techniques such as silica gel,ODS,Sephadex-LH 20,Pre-HPLC,their structures was elucidated by spectral data analysis.Compound 4 was isolated from Lauraceae plants for the first time.

Linderae Radixchemical constituentssesquiterpenoidseudesmane-typelindenane-type

李业生、白旭岚、许红涛、侴桂新

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上海中医药大学中药研究所,上海 201203

乌药 化学成分 倍半萜 桉叶烷型 钓樟烷型

"重大新药创制"科技重大专项子课题

2019ZX09735002-004

2024

天然产物研究与开发
中国科学院成都文献情报中心

天然产物研究与开发

CSTPCD北大核心
影响因子:0.783
ISSN:1001-6880
年,卷(期):2024.36(4)
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