摘要
研究乌药的化学成分.采用硅胶、ODS、Sephadex LH-20、制备液相等多种色谱分离技术进行分离纯化,通过波谱数据分析进行结构鉴定.从乌药90％乙醇提取物中分离得到4个倍半萜,分别鉴定为linderaggredin B1(1)、乌药酮酸A(2)、乌药酮酸B(3)、chlorahupetolide K(4),其中化合物1～3为新化合物,化合物4为首次从樟科中分离得到.
Abstract
To study the chemical constituents of Linderae Radix,three new compounds,named linderaggredin B1(1),linde-nonic acid A(2),and lindenonic acid B(3),along with one know compound chlorahupetolide K(4)were isolated from the 90％EtOH extract of Linderae Radix by various chromatographic techniques such as silica gel,ODS,Sephadex-LH 20,Pre-HPLC,their structures was elucidated by spectral data analysis.Compound 4 was isolated from Lauraceae plants for the first time.
基金项目
"重大新药创制"科技重大专项子课题(2019ZX09735002-004)
维普
万方数据