Secondary metabolites from the endophytic Chaetomium sp.of Dioscorea opposita
In this study,the secondary metabolites of an endophytic Chaetomium sp.L-45 from Dioscorea opposita were isola-ted and identified.The ethyl acetate extract of the rice fermentation of the fungus were separated by silica gel column chroma-tography,Sephadex LH-20,semi-preparative High-performance liquid chromatography,etc.,and the chemical structures of the compounds were identified by NMR and HR-ESI-MS analysis.As a result,four compounds were isolated and identified as 3,4-dimethoxy-5-hydroxy-6-propyl-benzoic acid(1),5-isoprenylindole-3-carboxylic acid(2),lecanorin(3),and ergosterol(4).Among them,compound 1 is a new compound,compounds 2 and 3 were isolated from genus Chaetomium for the first time.
Chaetomium sp.secondary metabolitesextraction and isolationstructure elucidation
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