Research progress on chemical compounds and pharmacological effects of Euonymus alatus(Thunb.)Siebold and predictive analysis on quality markers
Euonymus alatus(Thunb.)Siebold is considered as the wing-like appendage or wing-like branch,which was first recorded in the Shennong's Herbal Classic,is classified as a middle-grade herb with the effects of promoting blood circulation,dispelling blood stasis,killing parasites,and relieving pain.Modern pharmacological studies have shown that it has pharmaco-logical effects such as lowering blood glucose,anti-tumor,anti-inflammatory,analgesic,antibacterial,antioxidant,and antiviral effects,and its active ingredients are rich,and most of the current studies are focused on the flavonoid and terpenoid com-pounds.This article provides a comprehensive review of the chemical composition,pharmacological effects,toxicity,and other aspects of E.alatus.Based on the plant's phylogenetic relationship,the effectiveness of its chemical components,and the de-tectability of its chemical composition,speculations and analyses are made on the potential quality markers(Q-Marker)of E.alatus.It is preliminarily predicted that components such as rutin,quercetin,hesperidin,catechins,β-sitosterol,euonymuditer-pene A,11-keto-β-boswellic acid,etc.can be potential quality markers of E.alatus.This review aims to provide scientific evi-dence for the quality control and standardized clinical use of E.alatus.
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