As an important amino acid,glycine is widely used in pesticide,medicine,food and feed,etc.It is of great practical significance to study the synthesis method of glycine.The research progress of glycine chemical synthesis methods(chloro-acetic acid ammonolysis method,Strecker method,aminoacetonitrile method,hydantion method,alcohol ammoxidation method and methyl hydroxyacetate method,respectively)and biosynthesis methods(using aminoacetonitrile,carbon dioxide+ammonia as raw materials,respectively)were reviewed.The advantages and disadvantages of each method were analyzed and compared.The future development of glycine synthesis methods was also prospected.
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