摘要
甘氨酸作为一种重要氨基酸,广泛应用于农药、医药、食品和饲料等领域,研究甘氨酸的合成方法具有重要的现实意义.综述了甘氨酸的化学合成方法(分别为氯乙酸氨解法、施特雷克法、氨基乙腈法、直接海因法、醇氨氧化法和羟基乙酸甲酯法)和生物合成方法(分别以氨基乙腈、二氧化碳+氨气为原料)的研究进展,深入分析和对比了各方法的优点与缺点,并对甘氨酸合成方法未来的发展进行了展望.
Abstract
As an important amino acid,glycine is widely used in pesticide,medicine,food and feed,etc.It is of great practical significance to study the synthesis method of glycine.The research progress of glycine chemical synthesis methods(chloro-acetic acid ammonolysis method,Strecker method,aminoacetonitrile method,hydantion method,alcohol ammoxidation method and methyl hydroxyacetate method,respectively)and biosynthesis methods(using aminoacetonitrile,carbon dioxide+ammonia as raw materials,respectively)were reviewed.The advantages and disadvantages of each method were analyzed and compared.The future development of glycine synthesis methods was also prospected.
基金项目
陕西省重点研发计划(2024GX-YBXM-508)
陕西延长石油(集团)有限责任公司科技项目(ycsy2023ky-A-07)
国家科技期刊平台
NSTL
万方数据