Value of TDI-Tei index combined with serum NT-proBNP levels in evaluation of prognosis in patients with acute myocardial infarction
Objective:To investigate the predictive value of Tissue Doppler imaging-Tei Index(TDI-Tei index)combined with serum N-terminal pro-B-type brain natriuretic peptide(NT-proBNP)on long-term prognosis in patients with acute myocardial infarction(AMI)after percutaneous coronary intervention(PCI).Methods:A total of 201 AMI patients who came to Jinan People's Hospital for emergency PCI from March 1,2021 to June 30,2022 were selected as study subjects.For the following 12 months after the operation,patients were divided into the occurrence group(n = 50)and the non-occurrence group(n = 151)according to the occurrence of Major adverse cardiovascular events(MACEs)after PCI.Multifactorial logistic regressivity analysis was used to analyze relationship between TDI-Tei index,serum NT-proBNP levels and the occurrence of MACEs after PCI in patients with AMI period.Receiver operating characteristic(ROC)curve was used to analyze the predictive value of the TDI-Tei index,serum NT-proBNP levels and TDI-Tei index combined with serum NT-proBNP levels for MACEs in AMI patients after PCI.Results:Age,Door-Wire time,diabetes mellitus,coronary Gensini score,postoperative rhythm,cardiac troponin I(cTnI),uric acid,Tei index,and NT-proBNP in occurrence group were significantly higher than those of non-occurrence group,left ventricular ejection fraction was lower in the occurrence group than that in the non-occurrence group(P<0.001).Multivariate logistic regression analysis showed that postoperative heart rate,Tei index and NT-proBNP were independent predictors of the development of MACEs within 12 months after PCI in patients with AMI(P<0.001).ROC curve analysis indicated that the area under the curve(AUC)of MACEs predicted by serum NT-proBNP was 0.86,with a sensitivity of 76%and a specificity of 82.8%.The TDI-Tei index had an AUC of 0.940 with a sensitivity of 80%and a specificity of 94.7%.The combined prediction of the two indices had an much higher AUC of 0.961 with a sensitivity of 86%and a specificity of 97.4%.Conclusion:TDI-Tei index and serum NT-proBNP are independent predictors of MACEs within 12 months in AMI patients after PCI,TDI-Tei index combined with serum NT-proBNP has shown better predictive value for MACEs.
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