A systematic review and Meta-analysis of low-frequency repetitive transcranial magnetic stimulation in the treatment of aphasia after stroke
Objective:To investigate the clinical efficacy of low-frequency repetitive transcranial magnetic stimulation in the treatment of aphasia after stroke through Meta-analysis.Methods:From the establishment of the database to October 2023,articles on transcranial magnetic stimulation in the treatment of aphasia after stroke were searched from eight literature databases:CNKI,China Biomedical Literature Database,Wanfang Database,VIP database,PubMed,Cochrane Library,Embase and Web of Science.After literature screening,Meta-analysis was performed using Revman5.4 software.Results:A total of seven randomized controlled trials were included,involving 258 patients.Results:Meta-analysis showed that the CCAT score of the intervention group was better than that of the control group after receiving low-frequency repetitive transcranial magnetic stimulation(MD = 1.50,95%CI:1.046,1.960,P<0.001),among which,session(MD = 1.62,95%CI:0.60,2.63,P = 0.002).Description(MD = 1.86,95%CI:1.30,2.42,P<0.001),(MD = 2.54,95%CI:1.96,3.12,P<0.001),repeat(MD = 0.99,95%CI:0.45,1.52,P<0.001),spontaneous writing(MD = 1.28,95%CI:0.81,1.75,P<0.001),match(MD =-0.41,95%CI:-0.74,-0.08,P = 0.01).WAB-AQ score no statistical significance(MD =-2.44,95%CI:-25.33,20.45,P = 0.83).Conclusion:Low-frequency repetitive transcranial magnetic stimulation can effectively improve the speech function of patients with aphasia after stroke in terms of conversation,description,expression,repetition and spontaneous writing.
aphasialow frequency repetitive transcranial magnetic stimulationstrokeMeta-analysis
NETL
NSTL
万方数据
维普
