Correlation analysis between short-term exposure to air pollution and blood glucose in hypertensive patients in Hefei City
Objective:Epidemiological studies have shown that air pollution exposure has been associated with abnormal blood glucose,but limited studies have examined the associations in hypertensive patients.We aimed to examine the associations of exposure to air pollution with blood glucose in hypertensive patients.Methods:We had identi fi ed patients who were previously diagnosed as hypertension from the records of physical examination data of a tertiary hospital in Anhui Province from January to December 2021.We has used generalized additive models to estimate adverse effects of air pollution on blood glucose in hypertensive patients.A total of 8913 patients were enrolled in this study.Results:The results showed that short-term exposure to O3 was significantly and positively correlated with blood glucose levels in hypertensive patients.Specifically,it was statistically significant at Lag6 to Lag15 and Lag0-8 to Lag0-15.The O3 had the greatest effect on blood glucose in hypertensive patients when the cumulative lag was 15 days(lag0-15).For every 10 μg/m3 increase of the concentration O3,the abnormal blood glucose increased by 16.8%(95%CI:1.056-1.291).In addition,the stratified analyses by gender,age,and body mass index(BMI)showed that O3 had a more significant effect on blood glucose in females,those in the≥60 years age group,and those with weight in the normal range.Conclusion:In Hefei,the elevated levels of air pollution O3 is significantly associated with the increase of abnormal blood glucose levels in the hypertensive population.Among hypertensive patients,females,the elderly,and those of normal weight are more susceptible to O3.
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