首页|菌群失衡与子宫内膜异位症的相关性

菌群失衡与子宫内膜异位症的相关性

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子宫内膜异位症(endometriosis,EMS)是妇科的常见病、多发病,严重影响女性的生殖健康和生活质量.EMS的病因及发病机制尚不明确.研究显示,EMS患者存在菌群失衡,菌群通过导致炎症,影响免疫、内分泌和代谢等机制,参与EMS的形成和发展.菌群平衡是维持局部屏障功能正常的关键因素,恢复菌群稳态有利于改善EMS患者的预后.本文就EMS与菌群失衡的相关性做此综述,以期为EMS患者的临床诊疗提供新思路.
Relationship between bacterial imbalance and endometriosis
Being a common and frequently occurring gynecological disease,Endometriosis(EMS)seriously affects women's reproductive health and quality of life.Actually,the etiology and pathogenesis of EMS are still unclear at present.Research has revealed that patients suffering EMS have an imbalance in their microbiota,which participates the formation and development of EMS through mechanisms such as inflammation,immune,endocrine,and metabolic effects.Microbial balance is a key factor in maintaining normal local barrier function,and restoring bacterial homeostasis is beneficial for improving the prognosis of EMS patients.This article reviews the research progress on EMS and bacterial imbalance,hoping to provide new ideas for the clinical diagnosis and treatment of patients with EMS.

Endometriosisdysbiosisintestinal microbiotainflammationmicrobial therapy

侯刘静、李佳婷、韦玉艳、姜景岩

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山东第一医科大学(山东省医学科学院)研究生部,山东 济南 250117

山东第一医科大学附属中心医院妇科,山东 济南 250014

子宫内膜异位症 菌群失衡 肠道菌群 炎症 菌群治疗

2024

山东第一医科大学(山东省医学科学院)学报
泰山医学院

山东第一医科大学(山东省医学科学院)学报

影响因子:0.6
ISSN:2097-0005
年,卷(期):2024.45(6)
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