The value of transthoracic echocardiography in evaluating pulmonary hypertension compared to right heart catheterization examination:a single center study
Objective:To evaluate the consistency of non-invasive transthoracic echocardiography(TTE)in evaluating pulmonary hypertension(PH)and right heart catheterization.Methods:A retrospective analysis was conducted on 249 patients diagnosed with suspected pulmonary hypertension after right heart catheterization(RHC)in Qilu Hospital,Shandong University from January 2018 to June 2021.The diagnostic PH standard was mPAP>20 mmHg measured by RHC.ROC curve,Kappa consistency analysis,and Bland Altman consistency analysis were used to evaluate the accuracy of echocardiography in evaluating PH and its consistency with RHC.Results:The correlation between SPAP and mPAP measured by the two methods was statistically significant(rSPAP=0.800,rmPAP=0.744,P<0.001).The paired sample t-test showed that the difference in SPAP measured between the two was not statistically significant(P>0.05),while the difference in mPAP measured between the two was statistically significant(P<0.05).The ROC curve determines the reliability of SPAP screening for PH in echocardiography,with AUC=0.964,maximum Youden index=0.864,sensitivity=0.912,specificity=0.952.The ultrasound measured SPAP cutoff value was 38.5 mmHg.The Kappa values of TTE SPAP and mPAP screening for PH and RHC were 0.844 and 0.825,respectively.According to the Bland Altman consistency analysis,the detection values of TTE SPAP and RHC SPAP are Bias=0.36,with a 95%limits of agreement(LoA):-29.22～29.94,and 235(94.38%)points located within the 95%consistency limit.TTE mPAP and RHC mPAP bias=-2.98,with a 95%LoA:-20.66～14.69,and a total of 235(94.38%)points within the 95%consistency threshold.Conclusion:The correlation between mPAP and SPAP measured by TTE and RHC in our center is good,and it has high sensitivity and specificity for screening PH.
万方数据
维普
