Comparison of the sedative effect of remazolam and propofol in the imaging examination of children
Objective:To compare the sedative effects of remazolam and propofol in children with CT,MRI,etc.Methods:A total of 120 children who received imaging examination in Taian Maternal and Child Health Hospital from February 2023 to February 2024 were selected as research objects and were divided into observation group and control group by digital random method,with 60 cases in each group.The observation group was anesthetized with remazolam 0.3mg/kg,while the control group was anesthetized with propofol 2 mg/kg.Comparing the anesthetic effects of the two groups,average arterial pressure(MAP),heart rate(HR),blood oxygen saturation(SpO2),BIS value and the occurrence of adverse reactions were measured before anesthesia(T1),5min after anesthesia(T2),10min after anesthesia(T3),10min after examination(T4)and 20 min after examination(T5).Results:Compared with the control group,the effect time of anesthesia in the observation group was longer and the recovery time was shorter(P<0.05).At T2～T4,the values of MAP,HR,SpO2 and BIS in observation group were significantly higher than those in control group(P<0.05).There were no significant differences in MAP,HR,SpO2 and BIS values between the observation group and the control group at T1 and T5(P>0.05).There was no significant difference in the incidence of intraoperative body movement,dizziness,nausea and vomiting after recovery between the two groups(P>0.05).Conclusion:Compared with propofol,remazolam has better sedative effect and rapid recovery,less influence on circulation and respiration,and shorter duration of anesthesia.
万方数据
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