Progress in the study of changes in peripheral blood lymphocyte levels in non-small cell lung cancer and its relationship with prognosis
Lung cancer is the malignant tumor with the highest morbidity and mortality rate in China.Surgery,radiotherapy,and chemotherapy were the primary means of treatment for non-small cell lung cancer in the past.Immunotherapy and targeted therapy,such as immune checkpoint inhibitors against tumor immune escapealso play a vital role in its treatment.However,some patients are not sensitive to the treatment,so finding biomarkers to predict the efficacy of treatment is significant in achieving the precision treatment of lung cancer.Peripheral blood lymphocytes are critical to human systemic immunity as an essential complement of immune cells in the tumor microenvironment.In this paper,we systematically review the changes of peripheral blood lymphocytes in the development of lung cancerduring and after treatmentto further understand the progression of non-small cell lung cancer,thusproviding new ideas for developing therapeutic strategies.
万方数据
维普
