Research progress of choroidal vascular biomarkers in diabetic macular edema
Diabetic macular edema(DME)is a manifestation of diabetic retinopathy(DR),which can occur at any stage of DR and is one of the most common causes of vision loss in patients with DR.The choroid is the only source of blood supply to the macular fovea,so choroidal abnormalities can damage retinal function.The commonly used choroidal biomarkers are subfoveal choroidal thickness(SFCT)and choroidal vascularity index(CVI).SFCT and CVI reflect the choroidal blood flow,especially CVI,which has a great application prospect in monitoring the progress of DME and evaluating the prognosis.Understanding the baseline choroidal characteristics and the changes of choroidal vessels after anti-vascular endothelial growth factor(VEGF)treatment has important guiding significance for evaluating the therapeutic effect and prognosis of DME.
diabetic macular edemaanti-vascular endothelial growth factorsubfoveal choroidal thicknesschoroidal vascularity index