首页|蛋白质组学在胃癌生物学标记物研究中的应用

蛋白质组学在胃癌生物学标记物研究中的应用

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胃癌是消化道常见恶性肿瘤,早期诊断和早期治疗是改善患者预后的关键.近年来,应用蛋白质组学技术,通过分析、比较胃癌中异常表达的蛋白质,已发现一系列与胃癌发生、发展相关的蛋白,这些蛋白有潜力成为胃癌早期诊断和患者预后预测的生物学标记物.本文对近年来胃癌相关蛋白质组学生物学标记物的研究进展作一综述.
Application of Proteomics in Research of Biomarkers for Gastric Cancer
Gastric cancer is one of the most commonly seen malignant tumors in digestive tract.Early diagnosis and treatment is crucial for the improvement of patients'survival.By analyzing the proteins aberrantly expressed in gastric cancer using proteomics technologies,a series of proteins that are strongly related to the occurrence and development of gastric cancer have been identified,which are promising to be applied for the early diagnosis and prediction of patients' prognosis.This article reviewed the recent advances in research on proteomic biomarkers for gastric cancer.

Stomach NeoplasmsProteomicsBiological MarkersDiagnosisPrognosis

兰庆芝、马静静、董卫国

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武汉大学人民医院消化内科 430060

胃肿瘤 蛋白质组学 生物学标记 诊断 预后

2017

胃肠病学
上海交通大学医学院附属仁济医院

胃肠病学

CSTPCD
影响因子:1.217
ISSN:1008-7125
年,卷(期):2017.22(2)
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