摘要
目的：探讨不同类型钙化对超声诊断甲状腺癌的诊断价值。方法回顾性分析108例（232个）甲状腺结节患者的临床资料，以病理结果为金标准，分析甲状腺结节内钙化与甲状腺癌的相关性。结果在232个甲状腺结节患者中，恶性结节98个（42．2％），良性结节134个（57．8％）。98个恶性结节伴钙化者79个（80．6％），134个良性结节伴钙化者82个（61．2％）；其中在恶性结节中伴有微小钙化者74个（93．7％），在良性结节伴有微小钙化者13个（15．9％）。二者对比，差异具有统计学意义（P＜0．05）。钙化诊断甲状腺恶性结节的敏感性为49．1％（79／161），阳性预测值为80．6％（79／98）；微小钙化诊断甲状腺恶性结节的敏感性为85．1％（74／87），阳性预测值为93．7％（74／79）。结论甲状腺结节内钙化灶，特别是微小钙化对甲状腺癌的诊断具有重要意义。
Abstract
Objective To investigate the value of calcification in diagnosis of thyroid carcinoma with ultra-sound.Methods The clinical information of 232 thyroid nodules of 108 patients were analyzed retrospectively,with pa-thology as the gold standard,correlation of calcification with thyroid carcinoma was analyzed.Results In the 232 thyroid nodules,the malignant nodules were 98(42.2%),and the benign nodules were 134(57.8%).In 98 malignant nodules, 79(80.6%) nodules were found with calcifications,82(61.2%) benign nodules were found with calcifications.In ma-lignant nodules,74(93.7%) nodules were found with micro calcifications;In benign nodules,13(15.9%) nodules be-nign nodules were found with micro calcifications.The difference was statistically significant.The sensitivity of calcifica-tion to diagnosis of malignant thyroid nodules was 49.1%(79/161),positive predictive value was 80.6%(79/98). While the sensitivity of microcalcification to diagnosis of malignant thyroid nodules was 85.1%(74/87),positive predic-tive value was 93.7%(74/79) .Conclusion The calcification especially microcalcification in thyroid nodules has great value to diagnosis of thyroid carcinoma.
NETL
NSTL
维普
万方数据