Objective To analyze the subatherosclerosis and related factors in elderly type 2 diabetes mellitus(T2DM)patients with early chronic kidney disease.Methods From January 2019 to August 2022,2020 patients with type 2 diabetes who were≥60 years old in Qingdao Chengyang District People's Hospital were studied,including 1380 patients without CKD(non CKD group)and 640 patients with CKD(CKD group).The general clinical indicators,biochemical detection indicators,carotid artery intima-media thickness(CIMT),carotid ar-tery plaque formation and brachial ankle pulse wave velocity(baPWV)of the two groups were compared.Results The duration of diabetes in CKD group was longer than that in non CKD group,the complication rate of hypertension,retinopathy and peripheral neuropathy was higher than that in non CKD group,and the SGLT2 inhibitor was higher than that in non CKD group(P＜0.05);The levels of CRP,SBP,TG and UAER/CR in CKD group were higher than those in non CKD group(P＜0.05);The baPWV,mean CIMT,carotid plaque formation ratio in CKD group were higher than those in non CKD group(P＜0.01);CRP,SBP,TG,UACR were risk factors for subclinical atherosclerosis in eld-erly type 2 diabetes patients with early chronic kidney disease(P＜0.05).Conclusion The elderly type 2 diabetes mellitus(T2DM)with a long course of disease and early chronic kidney disease has a high complication rate of hypertension,retinopathy and peripheral neuropathy.It is more likely to have abnormal atherosclerosis indicators,and has a high risk of atherosclerosis and cardiovascular events.We should pay at-tention to the control of blood pressure,blood lipids,urinary protein,and inflammatory reaction.
维普
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