Objective To explore the clinical application value of specific enolase(NSE),erythrocyte sedimentation rate(ESR),and C-reactive protein(CRP)in pediatric pneumonia.Methods One hundred and fifty-three children with pneumonia admitted to Weifang People's Hospital from September 2020 to June 2023 were selected as the experimental group,including 85 cases of Mycoplasma pneumoniae pneumonia(MP+)group,78 cases of non Mycoplasma pneumoniae pneumonia(MP-)group,and 22 cases of severe pneumonia.One hundred and thirty-one cases of common(mild)pneumonia were selected,and 63 children who underwent outpatient health examinations during the same period were selected as the control group.Measure the serum NSE,ESR,and CRP levels of children in each group,and analyze and process the experimental data using SPSS 25.0 software.Results The serum NSE,ESR,and CRP of the case group were higher than those of the control group(P＜0.01).There was no difference in serum NSE and ESR between the MP+group and the MP-group(P＞0.05),but both were higher than the control group(P＜0.05).The CRP of the MP-group was higher than that of the MP+group and the control group,while there was no difference in CRP between the MP+group and the control group(P＞0.05).The serum NSE and CRP in the severe pneumonia group were higher than those in the mild pneumonia group(P＜0.05).The AUC value for diagnosing pneumonia is higher in NSE than in CRP and ESR.Conclusion The NSE level in children with pneumonia is significantly elevated,and compared to ESR and CRP,NSE has more important clinical significance in the diagnosis and disease assessment of pediatric pneumonia.
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