首页|Clinical outcomes of lung metastasectomy in patients with colorectal cancer

Clinical outcomes of lung metastasectomy in patients with colorectal cancer

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AIM:To investigate prognostic factors of survival following curative,non-palliative surgical removal of lung metastases secondary to colorectal cancer (CRC).METHODS:Between 1999 and 2009,a radical metastasectomy with curative intent was performed on lung metastases in 21 patients with CRC (15 male and 6 female; mean age:57.4 ± 11.8 years; age range:29-74years) who had already undergone primary tumour resection.RESULTS:The mean number of lung metastases ranged from one to five.The mean overall survival was 71 ±35 mo (median:25 mo).After adjusting for potential confounders,multivariable Cox regression analyses predicted only the number of lung metastases (1 vs ≥ 2;hazard ratio:7.60,95％ confidence interval:1.18-17.2,P =0.03) as an independent predictor of poor survival following lung resection for metastatic CRC.CONCLUSION:Resection of lung metastases is a safe and effective treatment in selected CRC patients with single lung metastases.

Lung metastasesColorectal cancerMetastasectomyPrognostic factorsSurvival

Omer Fatih Olmez、Erdem Cubukcu、Ahmet Sami Bayram、Unsal Akcali、Turkkan Evrensel、Cengiz Gebitekin

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Department of Medical Oncology, Uludag University Medical School, Bursa 16059, Turkey

Department of Thoracic Surgery, Uludag University Medical School, Bursa 16059,Turkey

Department of Internal Medicine, Uludag University Medical School, Bursa 16059, Turkey

2012

10.3748/wjg.v18.i7.662

世界胃肠病学杂志(英文版)
太原消化病研治中心

世界胃肠病学杂志(英文版)

SCI
影响因子：1.001
ISSN：1007-9327
年,卷(期)：2012.18(7)
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