首页|Routine blood tests to predict liver fibrosis in chronic hepatitis C

Routine blood tests to predict liver fibrosis in chronic hepatitis C

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AIM:To verify the usefulness of FibroQ for predicting fibrosis in patients with chronic hepatitis C,compared with other noninvasive tests.METHODS:This retrospective cohort study included 237 consecutive patients with chronic hepatitis C who had undergone percutaneous liver biopsy before treatment.FibroQ,aspartate aminotransferase (AST)/alanine aminotransferase ratio (AAR),AST to platelet ratio index,cirrhosis discriminant score,age-platelet index (API),Pohl score,FIB-4 index,and Lok's model were calculated and compared.RESULTS:FibroQ,FIB-4,AAR,API and Lok's model results increased significantly as fibrosis advanced (analysis of variance test:P < 0.001).FibroQ trended to be superior in predicting significant fibrosis score in chronic hepatitis C compared with other noninvasive tests.CONCLUSION:FibroQ is a simple and useful test for predicting significant fibrosis in patients with chronic hepatitis C.

Liver fibrosisNoninvasive testFibroQAspartate aminotransferaseAlanine aminotransferaseFIB-4 indexAspartate aminotransferase to platelet ratio indexLok's modelCirrhosis discriminant scorePohl score

Yung-Yu Hsieh、Shui-Yi Tung、Kamfai Lee、Cheng-Shyong Wu、Kuo-Liang Wei、Chien-Heng Shen、Te-Sheng Chang、Yi-Hsiung Lin

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Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Chiayi 613, Taiwan

Chang Gung University College of Medicine, Taoyuan 333, Taiwan

Chiayi School, Chang Gung Institute of Technology, Chiayi 613, Taiwan

Department of Pathology, Chang Gung Memorial Hospital, Chiayi 613, Taiwan

Department of Health Care Administration, Taiwan Shoufu University, Tainan 721, Taiwan

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Clinical Study Project XMRP

CMRPG 690081

2012

世界胃肠病学杂志(英文版)
太原消化病研治中心

世界胃肠病学杂志(英文版)

SCI
影响因子:1.001
ISSN:1007-9327
年,卷(期):2012.18(8)
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