首页|Evaluation of inflammatory activity in Crohn's disease and ulcerative colitis

Evaluation of inflammatory activity in Crohn's disease and ulcerative colitis

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Crohn's disease and ulcerative colitis evolve with a relapsing and remitting course.Determination of infiammatory state is crucial for the assessment of disease activity and for tailoring therapy.However,no simple diagnostic test for monitoring intestinal inflammation is available.Noninvasive markers give only indirect assessments of disease activity.Histopathological or endoscopical examinations accurately assess inflammatoryactivity,but they are invasive,time consuming and expensive and therefore are unsuitable for routine use.Imaging procedures are not applicable for ulcerative colitis.The usefulness of ultrasound and Doppler imaging in assessing disease activity is still a matter of discussion for Crohn's disease,and an increased interest in computed tomography enterograph (CTE) has been seen,mainly because it can delineate the extent and severity of bowel wall inflammation,besides detecting extraluminal findings.Until now,the available data concerning the accuracy of magnetic resonance enterography in detecting disease activity is less than CTE.Due to this,clinical activity indices are still commonly used for both diseases.

Crohn's diseaseUlcerative colitisInflammatory bowel diseaseDiagnostic testTherapyInflammatory markers

Eduardo Garcia Vilela、Henrique Osvaldo da Gama Torres、Fabiana Paiva Martins、Maria de Lourdes de Abreu Ferrari、Marcella Menezes Andrade、Aloísio Sales da Cunha

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Internal Medicine Department, Faculty of Medicine, Federal University of Minas Gerais, Minas Gerais 30130-100, Brazil

Gastroenterology Alfa Institute, Clinic Hospital, Federal University of Minas Gerais, Minas Gerais 30130-100, Brazil

Complementary Propedeutic Department, Faculty of Medicine, Federal University of Minas Gerais,Minas Gerais 30130-100, Brazil

Faculty of Medicine, Federal University of Minas Gerais, Minas Gerais 30130-100, Brazil

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2012

10.3748/wjg.v18.i9.872

世界胃肠病学杂志(英文版)
太原消化病研治中心

世界胃肠病学杂志(英文版)

SCI
影响因子：1.001
ISSN：1007-9327
年,卷(期)：2012.18(9)
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