首页|Pseudomelanosis duodeni associated with chronic renal failure

Pseudomelanosis duodeni associated with chronic renal failure

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Pseudomelanosis duodeni (PD) is a rare dark speckled appearance of the duodenum associated with gastrointestinal bleeding,hypertension,chronic heart failure,chronic renal failure and consumption of different drugs.We report four cases of PD associated with chronic renal failure admitted to the gastroenterology outpatient unit due to epigastric pain,nausea,melena and progressive reduction of hemoglobin index.Gastroduodenal endoscopy revealed erosions in the esophagus and stomach,with no active bleeding at the moment.In addition,the duodenal mucosa presented marked signs of melanosis; later confirmed by histopathological study.Even though PD is usually regarded as a benign condition,its pathogenesis and clinical significance is yet to be defined.

Pseudomelanosis duodeniChronic renal failureDiabetes mellitusAnti hypertensive drugsGastroduodenal endoscopy

Marcia Henriques de Magalh(a)es Costa、Maria da Gloria Fernandes Pegado、Cleber Vargas、Maria Elizabeth C Castro、Kalil Madi、Tiago Nunes、Cyrla Zaltman

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Gastroenterology Section, Department of Internal Medicine, Clementino Fraga Filho University Hospital, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-913,Brazil

Department of Pathology, Clementino Fraga Filho University Hospital, Universidade Federal do Rio de Janeiro,Rio de Janeiro 21941-913, Brazil

Hospital Clínic i Provincial/IDIBAPS, Barcelona 08036, Spain

2012

10.3748/wjg.v18.i12.1414

世界胃肠病学杂志(英文版)
太原消化病研治中心

世界胃肠病学杂志(英文版)

SCI
影响因子：1.001
ISSN：1007-9327
年,卷(期)：2012.18(12)
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