首页|Pancreatic schwannoma: Case report and an updated 30-year review of the literature yielding 47 cases
Pancreatic schwannoma: Case report and an updated 30-year review of the literature yielding 47 cases
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Pancreatic schwannomas are rare neoplasms.Authors briefly describe a 64-year-old female patient with cystic pancreatic schwannoma mimicking other cystic tumors and review the literature.Databases for PubMed were searched for English-language articles from 1980 to 2010 using a list of keywords,as well as references from review articles.Only 41 articles,including 47 cases,have been reported in the English literature.The mean age was 55.7 years (range 20-87 years),with 45% of patients being male.Mean tumor size was 6.2 cm (range 1-20 cm).Tumor location was the head (40%),head and body (6%),body (21%),body and tail (15%),tail (4%),and uncinate process (13%).Thirty-four percent of patients exhibited solid tumors and 60% of patients exhibited cystic tumors.Treatment included pancreaticoduodenectomy (32%),distal pancreatectomy (21%),enucleation (15%),unresectable (4%),refused operation (2%) and the detail of resection was not specified in 26% of patients.No patients died of disease with a mean follow-up of 15.7 mo (range 3-65 mo),although 5 (11%) patients had a malignancy.The tumor size was significantly related to malignant tumor (13.8 ± 6.2 cm for malignancy vs 5.5 ± 4.4 cm for benign,P =0.001)and cystic formation (7.9 ± 5.9 cm for cystic tumor vs 3.9± 2.4 cm for solid tumor,P =0.005).The preoperative diagnosis of pancreatic schwannoma remains difficult.Cystic pancreatic schwannomas should be considered in the differential diagnosis of cystic neoplasms and pseudocysts.In our case,intraoperative frozen section confirmed the diagnosis of a schwannoma.Simple enucleation may be adequate,if this is possible.