首页|Medical treatment for sphincter of oddi dysfunction: Can it replace endoscopic sphincterotomy?

Medical treatment for sphincter of oddi dysfunction: Can it replace endoscopic sphincterotomy?

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AIM:To report the results of a medical management of sphincter of oddi dysfunction (SOD) after an intermediate follow-up period.METHODS:A total of 59 patients with SOD (2 men and 57 women,mean age 51 years old) were included in this prospective study.After medical treatment for one year,the patients were clinically re-evaluated after an average period of 30 mo.RESULTS:The distribution of the patients according to the Milwaukee's classification was the following:11patients were type 1,34 were type 2 and 14 were type 3.Fourteen patients underwent an endoscopic sphincterotomy (ES) after one year of medical treatment.The median intermediate follow-up period was 29.8 ±3 mo (3-72 mo).The initial effectiveness of the medical treatment was complete,partial and poor among 50.8%,13.5% and 35%,respectively,of the patients.At the end of the follow-up period,37 patients (62.7%)showed more than 50% improvement.The rate of improvement in patients who required ES was not significantly different compared with the patients treated conservatively (64.2% vs 62.2%,respectively).CONCLUSION:Our study confirms that conservative medical treatment could be an alternative to endoscopic sphincterotomy because,after an intermediate follow-up period,the two treatments show the same success rates.

Sphincter of oddi dysfunctionCholecystectomyEndoscopic sphincterotomyBiliary scintigraphy

Véronique Vitton、Salah Ezzedine、Jean-Michel Gonzalez、Mohamed Gasmi、Jean-Charles Grimaud、Marc Barthet

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Department of Gastroenterology, H(o)pital Nord, Chemin des Bourrely, 13915 Marseille cedex 20, France

2012

世界胃肠病学杂志(英文版)
太原消化病研治中心

世界胃肠病学杂志(英文版)

SCI
影响因子:1.001
ISSN:1007-9327
年,卷(期):2012.18(14)
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