首页|Experience after 100 patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

Experience after 100 patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

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AIM:To investigate perioperative patient morbidity/mortality and outcome after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).METHODS:Of 150 patients 100 were treated with cytoreductive surgery and HIPEC and retrospectively analyzed.Clinical and postoperative follow-up data were evaluated.Body mass index (BMI),age and peritoneal carcinomatosis index (PCI) were chosen as selection criteria with regard to tumor-free survival and perioperative morbidity for this multimodal therapy.RESULTS:CRS with HIPEC was successfully performed in 100 out of 150 patients.Fifty patients were excluded because of intraoperative contraindication.Median PCI was 17 (1-39).In 89% a radical resection (CC0/CC1)was achieved.One patient died postoperatively due to multiorgan failure.Neither PCI,age nor BMI was a risk factor for postoperative complications/outcome according to the DINDO classification.In 9% Re-CRS with HIPEC was performed during the follow-up period.CONCLUSION:Patient selection remains the most important issue.Neither PCI,age nor BMI alone should be an exclusion criterion for this multimodal therapy.

Peritoneal carcinomatosisSingle-center experienceHyperthermic intraoperative chemotherapyComplicationsRisk assessmentSelection criteria

Ingmar K(o)nigsrainer、Derek Zieker、J(o)rg Glatzle、Olivia Lauk、Julia Klimek、Stephan Symons、Bj(o)rn Brücher、Stefan Beckert、Alfred K(o)nigsrainer

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Department of Surgery, University of Tübingen, Hoppe-Seyler-Strasse 3, D-72076 Tübingen, Germany

Center for Bioinformatics Tübingen, Sand 14,D-72076 Tübingen, Germany

2012

世界胃肠病学杂志(英文版)
太原消化病研治中心

世界胃肠病学杂志(英文版)

SCI
影响因子:1.001
ISSN:1007-9327
年,卷(期):2012.18(17)
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