首页|New reduced volume preparation regimen in colon capsule endoscopy

New reduced volume preparation regimen in colon capsule endoscopy

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AIM:To evaluate the effectiveness of our proposed bowel preparation method for colon capsule endoscopy.METHODS:A pilot,multicenter,randomized controlled trial compared our proposed "reduced volume method" (group A) with the "conventional volume method" (group B) preparation regimens.Group A did not drink polyethylene glycol electrolyte lavage solution (PEGELS) the day before the capsule procedure,while group B drank 2 L.During the procedure day,groups A and B drank 2 L and 1 L of PEG-ELS,respectively,and swallowed the colon capsule (PillCam COLON(R) capsule).Two hours later the first booster of 100 g magnesium citrate mixed with 900 mL water was administered to both groups,and the second booster was administered six hours post capsule ingestion as long as the capsule had not been excreted by that time.Capsule videos were reviewed for grading of cleansing level.RESULTS:Sixty-four subjects were enrolled,with results from 60 analyzed.Groups A and B included 31 and 29 subjects,respectively.Twenty-nine (94％) subjects in group A and 25 (86％) subjects in group B had adequate bowel preparation (ns).Twenty-two (71％) of the 31 subjects in group A excreted the capsule within its battery life compared to 16 (55％) of the 29 subjects in group B (ns).Of the remaining 22 subjects whose capsules were not excreted within the battery life,all of the capsules reached the left side colon before they stopped functioning.A single adverse event was reported in one subject who had mild symptoms of nausea and vomiting one hour after starting to drink PEG-ELS,due to ingesting the PEG-ELS faster than recommended.CONCLUSION:Our proposed reduced volume bowel preparation method for colon capsule without PEG-ELS during the days before the procedure was as effective as the conventional volume method.

Colon capsule endoscopyPolyethylene glycol electrolyte lavage solutionColon cleanlinessReduced volume preparation methodIsotonic magnesium citrate

Yasuo Kakugawa、Yutaka Saito、Shoichi Saito、Kenji Watanabe、Naoki Ohmiya、Mitsuyuki Murano、Shiro Oka、Tetsuo Arakawa、Hidemi Goto、Kazuhide Higuchi、Shinji Tanaka、Hideki Ishikawa、Hisao Tajiri

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Division of Screening Technology and Development, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104-0045, Japan

Endoscopy Division, National Cancer Center Hospital, Tokyo 104-0045, Japan

Department of Endoscopy, Jikei University School of Medicine, Tokyo 105-8461, Japan

Department of Gastroenterology, Osaka City University Graduate School of Medicine,Osaka 545-8685, Japan

Department of Therapeutic Medicine, Nagoya University Graduate School of Medicine,Nagoya 466-8560, Japan

Second Department of Internal Medicine, Osaka Medical College, Osaka 569-8686,Japan

Department of Endoscopy, Hiroshima University Hospital, Hiroshima 734-8551, Japan

Department of Molecular-Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-0841, Japan

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2012

10.3748/wjg.v18.i17.2092

世界胃肠病学杂志(英文版)
太原消化病研治中心

世界胃肠病学杂志(英文版)

SCI
影响因子：1.001
ISSN：1007-9327
年,卷(期)：2012.18(17)
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