首页|Association between body mass index and erosive esophagitis: A meta-analysis

Association between body mass index and erosive esophagitis: A meta-analysis

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AIM:To conduct a meta-analysis to estimate the determinants of the association between erosive esophagitis (EE) and body mass index (BMI).METHODS:We identified the studies using PubMed.Studies were selected for analysis based on certain inclusion and exclusion criteria.Data were extracted from each study on the basis of predefined items.Metaanalyses were performed to verify the risk factors,such as obesity and gender.RESULTS:Twenty-one studies were included in this systematic review.These studies demonstrated an association between increasing BMI and the presence of EE [95％ confidence interval (CI):1.35-1.88,overweight,odds ratio (OR) =1.60,P value homogeneity 0.003,95％ CI:1.65-2.55,obese,OR =2.05,P ＜0.01].The heterogeneity disappeared by stratifying for gender.No publication bias was observed in this metaanalysis by the Egger method.CONCLUSION:This analysis demonstrates a positive association between BMI and the presence of EE,especially in males.The risk seems to progressively increase with increasing weight.

Erosive esophagitisGastroesophageal reflux diseaseObesityBody mass indexMeta-analysis

Nan Cai、Guo-Zhong Ji、Zhi-Ning Fan、Yan-Feng Wu、Fa-Ming Zhang、Zhi-Fei Zhao、Wei Xu、Zheng Liu

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Department of Digestive Endoscopy and Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, 121 Jiangjiayuan Road, Nanjing 210011, Jiangsu Province, China

Department of Neurology, the Second Affiliated Hospital of Nanjing Medical University, 121 Jiangjiayuan Road,Nanjing 210011, Jiangsu Province, China

2012

10.3748/wjg.v18.i20.2545

世界胃肠病学杂志(英文版)
太原消化病研治中心

世界胃肠病学杂志(英文版)

SCI
影响因子：1.001
ISSN：1007-9327
年,卷(期)：2012.18(20)
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