首页|A pediatric non-protein losing Menetrier's disease successfully treated with octreotide long acting release

A pediatric non-protein losing Menetrier's disease successfully treated with octreotide long acting release

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Pediatric Menetrier's disease (MD) is an uncommon,acute,self-limited hypertrophic gastropathy characterized by enlarged gastric folds associated with epithelial hyperplasia and usually accompanied by protein losing gastropathy.Gastric cytomegalovirus infection is found in one third of MD children and its treatment is often associated with remission.Diagnosis often requires fullthickness biopsy due to inability to detect typical histological findings with conventional endoscopic biopsy.We report an uncommon case of non self-limited pediatric MD needing endoscopic mucosal resection for diagnosis which was then successfully treated with octreotide long-acting release (LAR).To the best of our knowledge,this is the first pediatric MD case successfully treated with octreotide LAR.Our experience suggests octreotide LAR as treatment for refractory MD before gastrectomy.

Menetrier's diseaseOctreotideEndoscopic mucosal resectionChildren

Giovanni Di Nardo、Salvatore Oliva、Marina Aloi、Federica Ferrari、Simone Frediani、Adriana Marcheggiano、Salvatore Cucchiara

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Department of Pediatrics, Pediatric Gastroenterology and Liver Unit, Sapienza University of Rome,00161 Rome,Italy

Department of Medical Science, Sapienza University of Rome, 00161 Rome, Italy

2012

世界胃肠病学杂志(英文版)
太原消化病研治中心

世界胃肠病学杂志(英文版)

SCI
影响因子:1.001
ISSN:1007-9327
年,卷(期):2012.18(21)
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