首页|Asymptomatic pancreatic lesions: New insights and clinical implications

Asymptomatic pancreatic lesions: New insights and clinical implications

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Despite great efforts in experimental and clinical research,the prognosis of pancreatic cancer (PC) has not changed significantly for decades.Detection of pre-invasive lesions or early-stage PC with small resectable cancers in asymptomatic individuals remains one of the most promising approaches to substantially improve the overall outcome of PC.Therefore,screening programs have been proposed to identify curable lesions especially in individuals with a familial or genetic predisposition for PC.In this regard,Canto et al recently contributed an important article comparing computed tomography,magnetic resonance imaging,and endoscopic ultrasound for the screening of 216 asymptomatic high-risk individuals (HRI).Pancreatic lesions were detected in 92 of 216 asymptomatic HRI (42.6%).The high diagnostic yield in this study raises several questions that need to be answered of which two will be discussed in detail in this commentary:First:which imaging test should be performed? Second and most importantly:what are we doing with incidentally detected pancreatic lesions? Which ones can be observed and which ones need to be resected?

Pancreatic cancerEarly-stage pancreatic cancerAsymptomatic high-risk individualsPreinvasive pancreatic lesionsCystic pancreatic tumorsScreeningComputed tomographyMagnetic resonance imagingEndoscopic ultrasound

Martin Loos、Christoph W Michalski、J(o)rg Kleeff

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Department of Surgery, Klinikum rechts der Isar, Technische Universit(a)t München, 81675 München, Germany

2012

世界胃肠病学杂志(英文版)
太原消化病研治中心

世界胃肠病学杂志(英文版)

SCI
影响因子:1.001
ISSN:1007-9327
年,卷(期):2012.18(33)
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