Current endoscopic approach to indeterminate biliary strictures

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NETL
NSTL
万方数据
维普

外文摘要：Biliary strictures are considered indeterminate when basic work-up,including transabdominal imaging and endoscopic retrograde cholangiopancreatography with routine cytologic brushing,are non-diagnostic.Indeterminate biliary strictures can easily be mischaracterized which may dramatically affect patient's outcome.Early and accurate diagnosis of malignancy impacts not only a patient's candidacy for surgery,but also potential timely targeted chemotherapies.A significant portion of patients with indeterminate biliary strictures have benign disease and accurate diagnosis is,thus,paramount to avoid unnecessary surgery.Current sampling strategies have suboptimal accuracy for the diagnosis of malignancy.Emerging data on other diagnostic modalities,such as ancillary cytology techniques,single operator cholangioscopy,and endoscopic ultrasonography-guided fine needle aspiration,revealed promising results with much improved sensitivity.

外文关键词：

Indeterminate strictureBile ductSingle operator cholangioscopeCholangioscopyEndoscopic ultrasoundEndoscopic retrograde cholangiopancreatographyBile duct strictureIndeterminate biliary strictureConfocal microscopyTranspapillary biopsyCho

作者：

David W Victor、Stuart Sherman、Tarkan Karakan、Mouen A Khashab

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作者单位：

Department of Medicine,Johns Hopkins Hospital, Baltimore, MD 21287, United States

Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, United States

Department of Medicine, Gazi University,06710 Ankara, Turkey

出版年：

2012

DOI：

10.3748/wjg.v18.i43.6197

世界胃肠病学杂志(英文版)