首页|Puncture injection of para-toluenesulfonamide combined with chemoembolization for advanced hepatocellular carcinoma

Puncture injection of para-toluenesulfonamide combined with chemoembolization for advanced hepatocellular carcinoma

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Hepatocellular carcinoma (HCC) is difficult to eradicate due to its resilient nature.Portal vein is often involved in tumors of large size,which exclude the patient from surgical resection and local ablative therapy,such as percutaneous ethanol injection (PEI) and radiofrequency ablation (RFA) because they were considered neither effective nor safe.Currently,there is almost no effective treatment for HCC of such condition.As a unique antitumor agent in form of lipophilic fluid for local injection,para-toluenesulfonamide (PTS) produces mild side effects while necrotizing the tumor tissues quickly and efficiently.Being largely different from both PEI and RFA therapies,PTS can disseminate itself in tumors more easily than other caustic agents,such as alcohol.So PTS may offer additional benefit to HCCs with vascular involvement.We herein describe a 70-year-old HCC patient who was treated with the combination of PTS injection and transcatheter arterial chemoembolization,resulting in a significantly improved clinical prognosis.

Hepatocellular carcinomaPara-toluenesulfonamideAntitumor agentTranscatheter arterial chemoembolizationTherapy

Qing He、An-Ren Kuang、Yong-Song Guan、Yue-Qing Liu

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Department of Oncology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China

Department of Nuclear Medicine, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China

2012

世界胃肠病学杂志(英文版)
太原消化病研治中心

世界胃肠病学杂志(英文版)

SCI
影响因子:1.001
ISSN:1007-9327
年,卷(期):2012.18(46)
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