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Tissue engineering for neuromuscular disorders of the gastrointestinal tract

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The digestive tract is designed for the optimal processing of food that nourishes all organ systems.The esophagus,stomach,small bowel,and colon are sophisticated neuromuscular tubes with specialized sphincters that transport ingested food-stuffs from one region to another.Peristaltic contractions move ingested solids and liquids from the esophagus into the stomach; the stomach mixes the ingested nutrients into chyme and empties chyme from the stomach into the duodenum.The to-and-fro movement of the small bowel maximizes absorption of fat,protein,and carbohydrates.Peristaltic contractions are necessary for colon function and defecation.

Neuromuscular disordersGastrointestinal tractDysfunctionEsophagusStomachSmall bowelColon

Kenneth L Koch、Khalil N Bitar、John E Fortunato

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Section on Gastroenterology, Department of Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27101, United States

Wake Forest Institute for Regenerative Medicine,Wake Forest School of Medicine, Winston-Salem, NC 27101,United States

NIH ResearchNIH ResearchNIH ResearchNIH Research

R01DK0716141RC1DK087151U01 DK073975-01

2012

世界胃肠病学杂志(英文版)
太原消化病研治中心

世界胃肠病学杂志(英文版)

SCI
影响因子:1.001
ISSN:1007-9327
年,卷(期):2012.18(47)
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