子宫肌瘤患者行高强度聚焦超声消融术对妊娠的影响
Effect of high-intensity focused ultrasound ablation surgery on pregnancy in patients with uterine fibroids
董欣 1庞晓卿 1任鹏 1杨晓丹 1杜娟 1秦丽欣 1张亚琴1
作者信息
- 1. 050500,石家庄市第六医院聚焦超声治疗科
- 折叠
摘要
目的 探讨子宫肌瘤患者行高强度聚焦超声消融术(FUAS)对妊娠的影响,并对影响妊娠的相关因素进行分析.方法 回顾性分析 2017-10 至 2021-01 在石家庄市第六医院经FUAS治疗且有生育需求的子宫肌瘤患者 136 例.根据术后是否妊娠分为妊娠组和未妊娠组,对比患者一般资料,并对影响术后妊娠的因素进行分析.结果 136 例患者经FUAS治疗后,72 例患者 81 次妊娠,妊娠率 59.56％(81/136);已分娩 72 次(52.94％,72/136 例),剖宫产 46 例,顺产 26 例,均未发生产后出血、子宫破裂等并发症.妊娠组与未妊娠组孕产史、肌瘤是否多发、肌瘤消融率、肌瘤缩小率及术后症状缓解方面,差异无统计学意义(P>0.05),两组间年龄、肌瘤类型及巨大肌瘤,差异有统计学意义(P<0.05),年龄小、浆膜下肌瘤、肌瘤<8 cm更容易妊娠.结论 FUAS治疗后患者妊娠率较高,且分娩安全;患者的年龄、肌瘤类型及巨大肌瘤是影响术后妊娠的重要因素.
Abstract
Objective To investigate the effect of high-intensity focused ultrasound ablation surgery(FUAS)on pregnancy in patients with uterine fibroids and to analyze the related factors affecting pregnancy.Methods A retrospective analysis was performed on 136 patients with uterine fibroids who were treated with FUAS and had fertility needs from October 2017 to January 2021 in No.6 Hospital of Shijiazhuang.The patients were divided into pregnancy group and non-pregnancy group after FUAS treatment according to whether they were pregnant or not.The general data of the patients were compared,and the factors affecting postoperative pregnancy were analyzed.Results After FUAS treatment,72 patients had 81 pregnancies,and the pregnancy rate was 59.56％(81/136).There were 72 deliveries(52.94％,72/136),46 cesarean sections(66.67％),26 normal deliveries,and no complications such as post-partum hemorrhage or uterine rupture.There was no statistical difference in the preoperative infertility history,the number of fi-broids,the proportion of fibroid ablation,the proportion of fibroid volume reduction or postoperative symptom improvement situation be-tween delivery group and non-pregnancy group,and statistical differences were found in the age,the type of fibroids and the volume of fibroids(P<0.05).Multivariate analysis implied that age,type of fibroids and volume of fibroids were the independence influencing factors of pregnancy.Conclusions The pregnancy rate is higher and the delivery is safe after FUAS treatment.The main influencing factors of pregnancy after FUAS treatment are age,type of fibroids and enormous fibroids.
关键词
子宫肌瘤/高强度聚焦超声/妊娠/分娩/影响因素Key words
uterine fibroid/high-intensity focused ultrasound/pregnancy/deliver/influencing factors引用本文复制引用
基金项目
河北省医学科学研究重点课题(20191417)
出版年
2024
国家科技期刊平台
NSTL
万方数据