Analysis of non-bacterial respiratory pathogen infection in 1300 children with acute re-spiratory tract infection
Objective To analyze pathogen detection in children with acute respiratory infection,and to provide evidence for clinical diagnosis,treatment and prevention.Methods The results of respiratory pathogen detection in throat swab samples of 1300 children with acute respiratory infection in the pediatric outpatient department of Beijing Aerospace General Hospital from September to November 2023 were retrospectively analyzed.The RNA of influenza A virus(INFA),influenza B virus(INFB),respiratory syncytial virus(RSV),parainfluenza virus-1(PIV-1),parainfluenza virus-3(PIV-3),adenovirus(ADV)and Mycoplasma pneumoniae(MP)were detected by PCR fluorescent probe.Results The total positive rate was 54.0%,and the positive rates of pathogen nucleic acid were INFA(24.6%),RSV(10.8%),MP(9.9%),ADV(8.3%),PIV1(2.6%),PIV 3(1.3%)and INFB(0.9%),59 cases(8.4%)had mixed infection,and both pathogens were detected at the same time.There was no significant difference in the total positive rate between different genders or different age groups(P>0.05).The positive rate of MP infection was the highest in the 7-14 year old group,the positive rate of INFB infection was the highest in the 4-6 year old group,and the positive rate of RSV and PIV3 infection was the highest in the 1-3 year old group,with statistically significant difference(P>0.05).There was no difference in the detection rate of other pathogens among different age groups.Conclusions INFA is the main pathogen in children with acute re-spiratory infection,there are mixed infections,and there are differences in pathogens among children of different age groups.
国家科技期刊平台
NSTL
万方数据
