Clinical effect of repetitive transcranial magnetic stimulation in patients with epilepsy af-ter stroke
Objective To investigate the clinical effect of repetitive transcranial magnetic stimulation(rTMS)in patients with epi-lepsy after stroke.Methods A total of 104 patients with post-stroke epilepsy treated in the Second Medical Center of PLA General Hospital from January 2021 to March 2023 were divided into observation group(n=52)and control group(n=52)using envelope method.The control group received routine treatment,while the observation group received rTMS treatment on the basis of the control group.The therapeutic effect and seizure status of the two groups were observed.Results The total effective rate of the observation group was 96.15%,which was better than that of the control group(P<0.05).After treatment,the frequency and duration of attacks in the observation group were(1.01±0.27)times/month and(2.20±0.74)min/time,respectively,which were lower than those in the control group(P<0.05).The Mini-mental State Examination(MMSE)score of the observation group after treatment was(25.54±2.01),which was higher than that of the control group(P<0.05),while the National Institutes of Health Stroke Scale(NIHSS)score was(6.14±1.82),which was lower than that of the control group(P<0.05).The scores of social function,physical function,psychological function,and material function on the GQOL-74 comprehen-sive assessment questionnaire for quality of life after treatment in the observation group were(86.65±9.55)points,(72.82±8.02)points,(80.03±8.33)points,and(83.34±7.94)points,respectively,which was higher than those in the control group(P<0.05).After treat-ment,serum homocysteine(Hcy),S100 calcium binding protein B(S100B),and neuron specific enolase(NSE)in the observation group were(7.22±1.93)μmol/L,(0.30±0.18)μg/L,and(5.65±1.12)μg/L,respectively,which were lower than those in the control group(P<0.05).Conclusions rTMS intervention has a good effect on patients with epilepsy after stroke,which is beneficial to the control of epi-lepsy and can improve the neurological and cognitive functions of the patients.
strokeepilepsyrepetitive transcranial magnetic stimulationclinical effectcognitive functions
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