Objective To observe the effect of preoperative quadratuslumborum block(QLB)on perioperative pain in patients undergoing laparoscopic radical colorectal cancer resection.Methods A total of 60 patients were selected,who were under general anesthesia for laparoscopic colorectal cancer resection.They were randomized to two groups:QLB group and control group,with 30 patients in each group.In the QLB group,QLB was performed under ultrasound guidance before operation,then general anesthesia was applied.The control group received general anesthesia only.The two groups of patients were given patient controlled intravenous analgesia(PCIA)after operation and monitored with a remote iPain-Free system.Heart rate(HR),mean artery pressure(MAP),sufentanil amount,and operation time were recorded during the operation.Visual analogue scale(VAS)scores were recorded on postoperative 1,3,6,24,and 48 h.The 24 h usage of PCIA,the total number and effective number of PCIA compressions,and the time of the first PCIA were recorded.Patients'satisfaction with postoperative analgesia was recorded.Pain scores were recorded at 3 months postoperative follow-up telephone visits.Results The HR and MAP of the QLB group during operation were lower than those of the control group,and the intraoperative sufentanil usage was significantly less in the QLB group than that in the control group(P<0.05).The VAS scores of patients in the QLB group at postoperative 1,3,and 6 h were significantly lower than those in the control group(P<0.05).The 24 h usage of PCIA and the total number of PCIA compressions in the QLB group were less than those in the control group,and the first PCIA time was later(P<0.05).Conclusion Preoperative ultrasound-guided QLB in laparoscopic colorectal cancer resection can play a good anesthetic synergy and good postoperative analgesic effect,and can optimize the perioperative pain management in patients undergoing laparoscopic radical resection of colorectal cancer.
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