A Fully-Printed Wearable Bandage-Based Electrochemical Sensor with pH Correction for Wound Infection Monitoring

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外文摘要：Wearable sensing systems have been designed to monitor health conditions in real-time by detecting analytes in human biofluids.Wound diagno-sis remains challenging,necessitating suitable materials for high-performance wearable sensors to offer prompt feedback.Existing devices have limitations in measuring pH and the concentration of pH-dependent electroactive species simultaneously,which is crucial for obtaining a comprehensive understanding of wound status and optimizing biosensors.Therefore,improving materials and analysis system accuracy is essential.This article introduces the first example of a flexible array capable of detecting pyocyanin,a bacterial virulence factor,while correcting dynamic pH fluctuations.We demonstrate that this combined sensor enhances accuracy by mitigating the impact of pH variability on pyo-cyanin sensor response.Customized screen-printable inks were developed to enhance analytical performance.The analytical performances of two sensitive sensor systems(i.e.,fully-printed porous graphene/multiwalled carbon nano-tube(CNT)and polyaniline/CNT composites for pyocyanin and pH sensors)are evaluated.Partialleast square regression is employed to analyze nonzero-order data arrays from square wave voltammetric and potentiometric measurements of pyocyanin and pH sensors to establish a predictive model for pyocyanin concentration in complex fluids.This sensitive and effective strategy shows potential for per-sonalized applications due to its affordability,ease of use,and ability to adjust for dynamic pH changes.

外文关键词：

PyocyaninBandagesWound monitoringBiosensorWearable device

作者：

Kanyawee Kaewpradub、Kornautchaya Veenuttranon、Husanai Jantapaso、Pimonsri Mittraparp-arthorn、Itthipon Jeerapan

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作者单位：

Center of Excellence for Trace Analysis and Biosensor,Prince of Songkla University,Hat Yai 90110,Songkhla,Thailand

Division of Physical Science,Faculty of Science,Prince of Songkla University,Hat Yai 90110,Songkhla,Thailand

The ijE Electrochemistry for All Laboratory,Prince of Songkla University,Hat Yai 90110,Songkhla,Thailand

Division of Biological Science,Faculty of Science,Prince of Songkla University,Hat Yai 90110,Songkhla,Thailand

Center of Excellence for Innovation in Chemistry,Faculty of Science,Prince of Songkla University,Hat Yai 90110,Songkhla,Thailand

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出版年：

2025

DOI：

10.1007/s40820-024-01561-8

纳微快报(英文)

上海交通大学

纳微快报(英文)

ISSN：2311-6706

年,卷(期)：2025.17(3)