Impact of short-term exposure to air pollution on older adults with chronic conditions in Shenzhen
Objective To investigate the effects of exposure to six air pollutants(PM2.5,PM10,SO2,NO2,CO,O3)on older adults with chronic conditions in Shenzhen.Methods Total of 741 individuals from a a community-based health examination survey were included from April 2021 to December 2022,and individuals'health examination data and environmental data in Shenzhen were collected.The population was divided into two groups based on the health examination records.Principal component regression and generalized estimating equations were employed to analysis the effects of six air pollutants on indicators for physical examination.Results After adjusting for all confounding factors,short-term exposure(PM10,PM2.5,CO,O3)and long-term exposure(PM10,PM2.5,CO,O3,NO2)of the first principal component was associated with the increased risk of conjugated bilirubin(β:0.25,95％CI:0.18～0.32;β:0.24,95％CI:0.16～0.32),and long-term exposure to second principal component(SO2)was associated with increased risk of conjugated bilirubin(β:0.17,95％CI:0.10～0.24)and decreased the risk of blood urea(β:-0.17,95％CI:-0.23～-0.11)among population with only one medical examination record.In the population that participated in two medical examinations,under short-term exposure to pollutants,PM2.5 concentrations increased by 10 μg/m3,conjugated bilirubin was increased 3.30 μmol/L(95％CI:2.33～4.30);PM10 concentrations increased by 10 μg/m3,triglycerides was increased 2.20 mmol(95％CI:1.30～3.10);NO2 concentrations increased by 10μg/m3,conjugated bilirubin and urinary creatinine were increased 3.20 μmol/L(95％CI:2.10～4.30)and 2.00 mmol/L(95％CI:1.10～2.90),but blood platelet decreased by 0.92x 108/L(95％CI:0.52×108～1.32×108).Under long-term exposure to pollutants;NO2 concentrations increased by 10 μg/m3,conjugated bilirubin was increased 1.90 μmol/L(95％CI:1.30～2.50);O3 concentrations increased by 10 μg/m3,conjugated bilirubin and unconjugated bilirubin were increased 1.00 μmol/L(95％CI:0.60～1.40)and 2.60(95％CI:1.60～3.60).Conclusion Exposure to air pollutants may cause the abnormal fluctuations on indicators of cardiovascular,renal or hepatic systems.Monitoring of air quality should be further strengthened,and the frequency of air quality monitoring should be increased.At the same time,health management should be further strengthened for the elderly.
Air pollutionElderlyIndicator for physical examinationChronic conditions
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NSTL
万方数据
